Biomaterial-Pushed Immunomodulation: Cell Biology-Based mostly Methods to Mitigate Extreme Irritation and Sepsis

 

Irritation is a vital part of all kinds of illness processes and oftentimes can enhance the deleterious results of a illness. Discovering methods to modulate this important immune course of is the idea for a lot of therapeutics below improvement and is a burgeoning space of analysis for each fundamental and translational immunology.

Along with growing therapeutics for mobile and molecular targets, using biomaterials to change innate and adaptive immune responses is an space that has just lately sparked important curiosity. Particularly, immunomodulatory exercise might be engineered into biomaterials to elicit heightened or dampened immune responses to be used in vaccines, immune tolerance, or anti-inflammatory purposes.

Importantly, the inherent physicochemical properties of the biomaterials play a major position in figuring out the noticed results. Properties together with composition, molecular weight, measurement, floor cost, and others have an effect on interactions with immune cells (i.e., nano-bio interactions) and permit for differential organic responses resembling activation or inhibition of inflammatory signaling pathways, floor molecule expression, and antigen presentation to be encoded.

Quite a few alternatives to open new avenues of analysis to grasp the methods through which immune cells work together with and combine info from their setting could present vital options wanted to deal with quite a lot of issues and illnesses the place immune dysregulation is a key inciting occasion. Nevertheless, to elicit predictable immune responses there’s a nice want for a radical understanding of how the biomaterial properties might be tuned to harness a designed immunological consequence.

This assessment goals to systematically describe the organic results of nanoparticle properties-separate from extra small molecule or biologic delivery-on modulating innate immune cell responses within the context of extreme irritation and sepsis. We suggest that nanoparticles symbolize a possible polypharmacological technique to concurrently modify a number of points of dysregulated immune responses the place single goal therapies have fallen brief for these purposes.

This assessment intends to function a useful resource for immunology labs and different related fields that want to apply the rising area of rationally designed biomaterials into their work.

 

Human Testosterone ELISA Kit
EH4850	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml

Human SPOCK2(Testican-2) ELISA Kit
EH2271	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human TEX101(testis expressed 101) ELISA Kit
EH12903	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens ;Sensitivity: 0.188 ng/ml

Human F-TESTO(Free Testoterone) ELISA Kit
EH3092	FN Test	96T	EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human ApoB48 ELISA Kit
EH4928	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75 ng/ml

Human APOM(Apolipoprotein M) ELISA Kit
EH2134	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human APOD(Apolipoprotein D) ELISA Kit
EH2135	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

Human ApoF(Apolipoprotein F) ELISA Kit
EH2657	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human APOE(Apolipoprotein E ) ELISA Kit
EH0549	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.75 ng/ml

Human APOL1(Apolipoprotein L1) ELISA Kit
EH1181	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human ApoB100(Apolipoprotein B100) ELISA Kit
EH0074	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5 ng/ml

Human APOA5(Apolipoprotein A-V) ELISA Kit
EH1952	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human APOA1(Apolipoprotein A-I ) ELISA Kit
EH0545	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Rat ApoC3(Apolipoprotein C3) ELISA Kit
ER0741	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 3.75 ng/ml

Human APOA4(Apolipoprotein A-IV) ELISA Kit
EH0618	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 2.813 ng/ml

Human APOB(Apolipoprotein B-100) ELISA Kit
EH0620	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875 ng/ml

Human APOA2(Apolipoprotein A-II) ELISA Kit
EH0633	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5 ng/ml

Accu-Tell COVID-19 IgG/IgM Rapid Test
GEN-B352-20tests	Accu test	20 tests	EUR 283.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Rabbit ApoC1(Apolipoprotein C1) ELISA Kit
ERB0012	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.094 ng/ml

Monkey ApoC3(Apolipoprotein C3) ELISA Kit
EMK0008	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Ape;Sensitivity: 0.938 ng/ml

Mouse APO-C1(Apolipoprotein C1) ELISA Kit
EM0844	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 37.5 ng/ml

Mouse APO-C4(Apolipoprotein C4) ELISA Kit
EM0845	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Human PDHA2(Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial) ELISA Kit
EH1149	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

T(Testosterone) ELISA Kit
EU0400	FN Test	96T	EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 0.188 ng/ml

Mouse Testosterone ELISA Kit
EM1850	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 0.188 ng/ml

Rat T(Testosterone) ELISA Kit
ER1462	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 0.188 ng/ml

Human BAX(Apoptosis regulator BAX) ELISA Kit
EH0669	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human APOH(Beta-2-glycoprotein 1 ) ELISA Kit
EH0531	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 28.125pg/ml

Bovine T(Testosterone) ELISA Kit
EB0049	FN Test	96T	EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Cattle;Sensitivity: 0.188 ng/ml

Human APOA1BP(Apolipoprotein A-I-binding protein) ELISA Kit
EH1180	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human FASL(Factor Related Apoptosis Ligand) ELISA Kit
EH0127	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human SIVA1(Apoptosis regulatory protein Siva) ELISA Kit
EH2267	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml

Human EGF ELISA kit (Quick Test)
E22-HC126QT.48	EnoGene	48T	EUR 495

Human EGF ELISA kit (Quick Test)
E22-HC126QT.96	EnoGene	96T	EUR 595

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)
GEN-402-25tests	All test	25 tests	EUR 292.8
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Human Apo A1-Ab(Anti-Apolipoprotein A1 Antibody) ELISA Kit
EH2655	FN Test	96T	EUR 628.92
Description: Method of detection: Sandwich ELISA, Double Antigen ;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml

Human PAWR(PRKC apoptosis WT1 regulator protein) ELISA Kit
EH10908	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human VEGF ELISA kit (Quick Test)
E22-HC108QT.48	EnoGene	48T	EUR 495

Human VEGF ELISA kit (Quick Test)
E22-HC108QT.96	EnoGene	96T	EUR 595

Human FAIM3(Fas Apoptotic Inhibitory Molecule 3) ELISA Kit
EH3035	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human PUMA(P53 Upregulated Modulator of Apoptosis) ELISA Kit
EH0250	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human NAIF1(Nuclear apoptosis-inducing factor 1) ELISA Kit
EH1223	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human CD94 ELISA Kit
EH7228	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human TIGAR ELISA Kit
EH4927	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human CD226 ELISA Kit
EH7177	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human EPAC2 ELISA Kit
EH8258	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human APAF1(Apoptosis Protease Activating Factor 1) ELISA Kit
EH2654	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human TRIM14 ELISA Kit
EH13190	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Spexin ELISA Kit
EH4349	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml

Human Irisin ELISA Kit
EH4702	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human PRSS36 ELISA Kit
EH4924	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human SHARPIN ELISA Kit
EH12274	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ASK-1(Apoptosis Signal Regulating Kinase 1) ELISA Kit
EH2670	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human SERPIND1 ELISA Kit
EH12199	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human Thrombin ELISA Kit
EH4141	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human Asprosin ELISA Kit
EH4176	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human KITLG(Kit ligand ) ELISA Kit
EH0514	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human Neopterin ELISA Kit
EH3413	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human CFLAR(CASP8 and FADD-like apoptosis regulator) ELISA Kit
EH1762	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml

Human Calprotectin ELISA Kit
EH4140	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375 ng/ml

Human Pre-S1 ELISA Kit
EH4111	FN Test	96T	EUR 571.5
Description: Method of detection: Qualitative ;Reacts with: Homo sapiens;Sensitivity: Qualitative

Human EZR(Ezrin) ELISA Kit
EH1471	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human TTN(Titin) ELISA Kit
EH1877	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human KL(Klotho) ELISA Kit
EH2184	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml

Human PP(Pepsin) ELISA Kit
EH3629	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

Human Rbx2(RNF7) ELISA Kit
EH4196	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human CRN(Corin) ELISA Kit
EH0097	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 45pg/ml

Human FUR(Furin) ELISA Kit
EH0143	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human REN(Renin) ELISA Kit
EH0268	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human AGRN(Agrin) ELISA Kit
EH1477	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human NDP(Norrin) ELISA Kit
EH1664	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human MEFV(Pyrin) ELISA Kit
EH2102	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human NES(Nestin) ELISA Kit
EH2140	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human AFM(Afamin) ELISA Kit
EH2493	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml

Human Des(Desmin) ELISA Kit
EH2944	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Activin A ELISA Kit
EH0028	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

Human LN(Laminin) ELISA Kit
EH0214	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human LEP(Leptin) ELISA Kit
EH0216	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human MK(Midkine) ELISA Kit
EH0229	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human NDN(Necdin) ELISA Kit
EH0866	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human NOG(Noggin) ELISA Kit
EH1051	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human ELN(Elastin) ELISA Kit
EH1505	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.281 ng/ml

Human GC(Glucagon) ELISA Kit
EH1944	FN Test	96T	EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human ACR(Acrosin) ELISA Kit
EH2014	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 3.75mIU/ml

Human RELN(Reelin) ELISA Kit
EH2121	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human APLN(Apelin) ELISA Kit
EH2174	FN Test	96T	EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

Human OGN(Mimecan) ELISA Kit
EH2412	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human MTL(Motilin) ELISA Kit
EH3393	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human TRY(Trypsin) ELISA Kit
EH3915	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human OSX(Osterix) ELISA Kit
EH4043	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Es(Estrogen) ELISA Kit
EH4184	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human OT(Oxytocin) ELISA Kit
EH4212	FN Test	96T	EUR 571.5
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human DCN(Decorin) ELISA Kit
EH0111	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.75 ng/ml

Human LUM(Lumican) ELISA Kit
EH0220	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human INS(Insulin) ELISA Kit
EH0374	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human FE(Ferritin) ELISA Kit
EH0382	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human HCRT(Orexin) ELISA Kit
EH1045	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human Aldolase B ELISA Kit
EH4806	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.281 ng/ml

Human SCT(Secretin) ELISA Kit
EH1210	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human BGN(Biglycan) ELISA Kit
EH1218	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human GAST(Gastrin) ELISA Kit
EH1397	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188pg/ml

Human PRX(Periaxin) ELISA Kit
EH1492	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human OPTC(Opticin) ELISA Kit
EH1604	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.9pg/ml

Human PLEC(Plectin) ELISA Kit
EH1770	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human FSCN1(Fascin) ELISA Kit
EH1915	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human VCL(Vinculin) ELISA Kit
EH1957	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human TNC(Tenascin) ELISA Kit
EH2027	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human OB(Obestatin) ELISA Kit
EH2063	FN Test	96T	EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human CMA1(Chymase) ELISA Kit
EH2077	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human ENHO(Adropin) ELISA Kit
EH2290	FN Test	96T	EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human CNX(Calnexin) ELISA Kit
EH2856	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

Human CPP(Copeptin) ELISA Kit
EH2880	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human MT(Melatonin) ELISA Kit
EH3344	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml

Human Pax(Paxillin) ELISA Kit
EH3511	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human PDCN(Podocin) ELISA Kit
EH3529	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human TPS(Tryptase) ELISA Kit
EH3906	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

Human ENG(Endoglin) ELISA Kit
EH0071	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human GHRL(Ghrelin) ELISA Kit
EH0355	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 28.125pg/ml

Human COR(Cortisol) ELISA Kit
EH0641	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.234 ng/ml

Human CAT(Catalase) ELISA Kit
EH0643	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human STH(Saitohin) ELISA Kit
EH0832	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human GSN(Gelsolin) ELISA Kit
EH0875	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 3.75 ng/ml

Human VIM(Vimentin) ELISA Kit
EH1166	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688 ng/ml

Human ASPN(Asporin) ELISA Kit
EH1174	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human S100 Protein ELISA Kit
EH4865	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Histone-H3 ELISA Kit
EH9123	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 46.875pg/ml

Human CFP(Properdin) ELISA Kit
EH1217	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human HRNR(Hornerin) ELISA Kit
EH1240	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human RNLS(Renalase) ELISA Kit
EH1250	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human MYOG(Myogenin) ELISA Kit
EH1256	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.375 ng/ml

Human STOM(Stomatin)ELISA Kit
EH12686	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human FLG(Filaggrin) ELISA Kit
EH1353	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human LGMN(Legumain) ELISA Kit
EH1372	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human SPAST(Spastin) ELISA Kit
EH15353	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human OCLN(Occludin) ELISA Kit
EH1674	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human NEO1(Neogenin) ELISA Kit
EH1782	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human Opi(Opiorphin) ELISA Kit
EH1927	FN Test	96T	EUR 681.12
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human HPX(Hemopexin) ELISA Kit
EH2031	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human UCN(Urocortin) ELISA Kit
EH2157	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human UTRN(Utrophin) ELISA Kit
EH2376	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human HDLBP(Vigilin) ELISA Kit
EH2505	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human his(Histamine) ELISA Kit
EH2552	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human Amylase Alpha ELISA Kit
EH2652	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.4mIU/ml

Human ARO(Aromatase) ELISA Kit
EH2665	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Human BCAN(Brevican) ELISA Kit
EH2693	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human BK(Bradykinin) ELISA Kit
EH2705	FN Test	96T	EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pg/ml

Human FG(Fibrinogen) ELISA Kit
EH3057	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human Hepc(Hepcidin) ELISA Kit
EH3221	FN Test	96T	EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75 pg/ml

Human CLU(Clusterin) ELISA Kit
EH0004	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml

Human CHEM(Chemerin) ELISA Kit
EH0092	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

 

4D Cell Biology: Adaptive optics lattice light-sheet imaging and AI powered massive information processing of reside stem cell-derived organoids

 

New strategies in stem cell 3D organoid tissue tradition, superior imaging, and massive information picture analytics now enable tissue-scale 4D cell biology however at present accessible analytical pipelines are insufficient for handing and analyzing the ensuing gigabytes and terabytes of high-content imaging information. We expressed fluorescent protein fusions of clathrin and dynamin2 at endogenous ranges in genome- edited human embryonic stem cells, which had been differentiated into intestinal epithelial organoids.

Lattice light-sheet imaging with adaptive optics (AO-LLSM) allowed us to picture massive volumes of those organoids (70 × 60 × 40 μm xyz) at 5.7 s/body. We developed an open-source information evaluation bundle termed pyLattice to course of the ensuing massive (∼60 Gb) film information units and to trace clathrin-mediated endocytosis (CME) occasions.

We then expressed fluorescent protein fusions of actin and tubulin in genome-edited induced human pluripotent stem cells, which had been differentiated into human cortical organoids. Utilizing the AO-LLSM mode on the new MOSAIC (Multimodal Optical Scope with Adaptive Imaging Correction) allowed us to picture neuronal migration deep within the organoid. We augmented pyLattice with a deep studying module and used it to course of the mind organoid information.

Frequent Sources of Irritation and Their Impression on Hematopoietic Stem Cell Biology

 

Objective of assessment: Inflammatory indicators have emerged as vital regulators of hematopoietic stem cell (HSC) operate. Particularly, HSCs are extremely conscious of acute modifications in systemic irritation and this influences not solely their division charge but additionally their lineage destiny. Figuring out how irritation regulates HSCs and shapes the blood system is essential to understanding the mechanisms underpinning these processes, in addition to potential hyperlinks between them.

 

Current findings: A widening array of physiologic and pathologic processes involving heightened irritation at the moment are acknowledged to critically have an effect on HSC biology and blood lineage manufacturing. Situations documented to have an effect on HSC operate embrace not solely acute and power infections but additionally autoinflammatory circumstances, irradiation harm, and physiologic states resembling getting older and weight problems.

 

Abstract: Recognizing the contexts throughout which irritation impacts primitive hematopoiesis is important to bettering our understanding of HSC biology and informing new therapeutic interventions in opposition to maladaptive hematopoiesis that happens throughout inflammatory illnesses, infections, and cancer-related issues.

 

 

293AAV Cell Line
AAV-100	Cell Biolabs	1 vial	EUR 405

293LTV Cell Line
LTV-100	Cell Biolabs	1 vial	EUR 405

293RTV Cell Line
RV-100	Cell Biolabs	1 vial	EUR 405

MCF7 [MCF-7] Cell Line
CL-0149	Elabscience Biotech	1×10⁶ cells/vial	EUR 420
Description: Homo sapiens, Human

293/GFP Cell Line
AKR-200	Cell Biolabs	1 vial	EUR 460

T47D/GFP Cell Line
AKR-208	Cell Biolabs	1 vial	EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

A549/GFP Cell Line
AKR-209	Cell Biolabs	1 vial	EUR 460

HeLa/GFP Cell Line
AKR-213	Cell Biolabs	1 vial	EUR 460

293/Cas9 Cell Line
AKR-5110	Cell Biolabs	1 vial	EUR 460

HeLa/Cas9 Cell Line
AKR-5111	Cell Biolabs	1 vial	EUR 460

NIH3T3/GFP Cell Line
AKR-214	Cell Biolabs	1 vial	EUR 460

NIH3T3/Cas9 Cell Line
AKR-5104	Cell Biolabs	1 vial	EUR 460

OVCAR-5/RFP Cell Line
AKR-254	Cell Biolabs	1 vial	EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

MCF-7-LUC cells
S0006002	Addexbio	One Frozen vial	EUR 420

PKCa Stable Expressing MCF-7 (MCF-7/PKCa20) Cell Line
T6115	ABM	1x10^6 cells / 1.0 ml	EUR 3950

Platinum-E Retroviral Packaging Cell Line, Ecotropic
RV-101	Cell Biolabs	1 vial	EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic
RV-103	Cell Biolabs	1 vial	EUR 770

Platinum-A Retroviral Packaging Cell Line, Amphotropic
RV-102	Cell Biolabs	1 vial	EUR 770

Total Protein - Murine Embryonic Stem Cell Line D3
CBA-305	Cell Biolabs	500 ?g	EUR 414
Description: Isolated from mouse ES-D3 cell line Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

MCF 10A Cell Line
CL-0525	Elabscience Biotech	1×10⁶ cells/vial	EUR 500
Description: Homo sapiens, Human

cDNA - Human Tumor Cell Line: MCF 7
C1255830	Biochain	40 reactions	EUR 424

Flavopiridol-Resistant MCF-7 Cell Line (FLV100)
T8033	ABM	1x10^6 cells / 1.0 ml	EUR 2950

Flavopiridol-Resistant MCF-7 Cell Line (FLV1000)
T8035	ABM	1x10^6 cells / 1.0 ml	Ask for price

Luc-Akt-PH Stable MCF7 Cell Line
T3160	ABM	1x10^6 cells / 1.0 ml	EUR 3950

Total RNA - Human Tumor Cell Line: MCF 7
R1255830-50	Biochain	50 ug	EUR 229

Genomic DNA - Human Tumor Cell Line: MCF 7
D1255830	Biochain	100 ug	EUR 282

Total Protein - Human Tumor Cell Line: MCF 7
P1255830	Biochain	1 mg	EUR 216

Membrane Protein - Human Tumor Cell Line: MCF 7
P3255830	Biochain	0.1 mg	EUR 311

Exosome derived from human breast cancer, noninvasive cell line (MCF-7 cell line)
Exo-CH06	Creative BioMart	Each	EUR 1249.5
Description: Exosome

Paraffin Tissue Section - Human Tumor Cell Line: MCF-7
T2255830	Biochain	5 slides	EUR 262

AAV2-Luc Control Virus
AAV-320	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 2.

AAV1-Luc Control Virus
AAV-321	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 1.

AAV3-Luc Control Virus
AAV-323	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 3.

AAV4-Luc Control Virus
AAV-324	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 4.

AAV5-Luc Control Virus
AAV-325	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 5.

AAV6-Luc Control Virus
AAV-326	Cell Biolabs	50 ?L	EUR 1221.6
Description: Luciferase control virus of AAV serotype 6.

Tissue, Section, Human Disease, Human Tumor Cell Line, MCF-7 (Paraffin)
MBS640859-5Slides	MyBiosource	5Slides	EUR 510

Tissue, Section, Human Disease, Human Tumor Cell Line, MCF-7 (Paraffin)
MBS640859-5x5Slides	MyBiosource	5x5Slides	EUR 2145

GAS(Luc) Report Cell Line-HeLa
ABC-RC099D	AcceGen	1 vial	Ask for price
Description: The GAS reporter (Luc)-HeLa cell line is designed to monitor the activity of IFN gamma-induced signal transduction pathways in cultured cells by measuring activated STAT1 homodimers. It contains a firefly luciferase gene driven by three copies of the IFN gamma-activated sites (GAS) located upstream of the minimal TATA promoter. IFNγ first binds to a heterodimeric receptor consisting of two chains, IFNGR1 and IFNGR2, causing its dimerization and the activation of specific Janus family kinases (JAK1 and JAK2). Two STAT1 molecules associate with this ligand-activated receptor complex and are activated by phosphorylation to form active homodimer. The active STAT1 homodimers translocate to the nucleus where they bind IFN gamma-activated sites (GAS) in the promoter of IFNγ inducible genes, including luciferase reporter gene.

GAL4 Report Cell Line(Luc)-HEK293
ABC-RC113D	AcceGen	1 vial	Ask for price
Description: The GAL4 Reporter (Luc) andndash; HEK293 Cell Line contains a firefly luciferase gene under the control of a multimerized GAL4 upstream activation sequence (UAS) stably integrated into HEK293 cells. The cell line does not contain any exogenous activators of the GAL4 reporter.

NFAT Reporter (Luc) - Jurkat Cell Line
60621	BPS Bioscience	2 vials	EUR 2295
Description: The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the_x000D_NFAT response element stably integrated into Jurkat cells. This cell line has been validated for_x000D_response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as_x000D_a control cell line for other NFAT reporter cell lines expressing various immune checkpoint_x000D_receptors.

GAL4 Reporter (Luc)-HEK293 Cell Line
60656	BPS Bioscience	2 vials	EUR 1095
Description: The GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of a multimerized GAL4 upstream activation sequence (UAS) stably integrated into HEK293 cells. The cell line does not contain any exogenous activators of the GAL4 reporter and can be used alongside BPS Cat. #60655 as a control.

Foxp3(Luc) Report Cell Line-Jurkat
ABC-RC106D	AcceGen	1 vial	Ask for price
Description: Human Foxp3 luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by a human Foxp3 promoter and an enhancer-like conserved noncoding sequence upstream of the Foxp3 promoter.

MCF-7 Human breast cancer, noninvasive cell line: >1x10^10 frozen exosomes
EXOP-100A-1	SBI	50 ug	EUR 409

STAT5 Reporter (Luc) - Ba/F3 Cell line
79772	BPS Bioscience	2 vials	EUR 2275
Description: The STAT5 Reporter (Luc)-Ba/F3 cell line is designed for monitoring STAT5 signal transduction pathways. It contains a firefly luciferase gene driven by the STAT5 response element located upstream of the minimal TATA promoter. After activation by cytokines or growth factors, endogenous STAT5 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)
CBA-325	Cell Biolabs	96 assays	EUR 1027.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)
CBA-325-5	Cell Biolabs	5 x 96 assays	EUR 4033.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric
CBA-135	Cell Biolabs	96 assays	EUR 715

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Colorimetric
CBA-135-5	Cell Biolabs	5 x 96 assays	EUR 3095

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric
CBA-140	Cell Biolabs	96 assays	EUR 750

CytoSelect™ Cell Transformation Assay (Cell Recovery Compatible), Fluorometric
CBA-140-5	Cell Biolabs	5 x 96 assays	EUR 3215

IRF Reporter (Luc) - THP-1 Cell line
79858	BPS Bioscience	2 vials	EUR 1810
Description: The Interferon Regulatory Factor (IRF) reporter (Luc)-THP-1 cell line is designed to study the activation and signaling of Cytosolic DNA Sensors (CDS) in human monocytic cell line THP-1. It contains a firefly luciferase gene driven by multimerized ISRE (Interferon Stimulated Response Element) located upstream of the minimal TATA promoter. _x000D_The cGAS-STING pathway acts to detect cytosolic DNA and induce an immune response. Briefly, upon binding DNA, the protein cGAS (cyclic GMP-AMP Synthase) triggers reaction of GTP and ATP to form cGAMP. cGAMP binds to STING (Stimulator of Interferon Genes) which triggers phosphorylation of IRF3 via TBK1. IRF3 can then bind to interferon-stimulated responsive elements (ISRE) in the nucleus and leads to IFN-α/β production. The IRF reporter (Luc)-THP-1 cell line is highly responsive to STING and CDS ligands.

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric, Trial Size
CBA-135-T	Cell Biolabs	24 assays	EUR 518.4
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

GR-GAL4 Report Cell Line(Luc)-HEK293
ABC-RC114D	AcceGen	1 vial	Ask for price
Description: The Glucocorticoid Receptor Pathway GAL4 Reporter (Luc) – HEK293 Cell Line contains a firefly luciferase gene under the control of glucocorticoid receptor ligand binding domain that is fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD-GR) stably integrated into HEK293 cells. This fusion construct activates firefly luciferase expression under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of DXMS and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway.

NF-κB Reporter (Luc) - HCT116 Cell Line
60623	BPS Bioscience	2 vials	EUR 1095
Description: NF- B luciferase reporter construct is stably integrated into the genome of HCT-116 cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κ B transcription factors bind to the DNA response elements to induce transcription of the luciferase gene._x000D_The NF- κB-luciferase/HCT-116 cell line is suitable for monitoring the activity of NF-κB signaling in response to stimulants such as the cytokines TNF and IL-1β, pathogen-associated molecular pattern (PAMP) (i.e. flagellin) or endogenous damage-associated molecular pattern (DAMP) molecules (i.e. NOD1 ligand) (see application references). It is also suitable for establishing cell-based screens for inhibitors that target specific NF-κB stimulating molecules. This cell line can be further modified to allow investigation of downstream NF-κB activities as a result of targeted genetic mutation(s).

NF-κB reporter (Luc) - HEK293 Cell line
60650	BPS Bioscience	2 vials	EUR 1365
Description: The NF-κB reporter (Luc) HEK293 cell line is designed to monitor nuclear factor Kappa B (NF-κB) activity. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene. The cell line has been functionally validated in response to human TNF-α, IL-1β, and IL-17.

NF-kB reporter (Luc) - HEK293 Cell line
GWB-PS76F8	GenWay Biotech	2X10(6)cells	Ask for price

Tissue, Total Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima)
MBS657022-1mg	MyBiosource	1mg	EUR 565

Tissue, Total Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima)
MBS657022-5x1mg	MyBiosource	5x1mg	EUR 2315

CytoSelect 96-Well Cell Transformation Assay (Cell Recovery Compatible, Fluorometric), Trial Size
CBA-140-T	Cell Biolabs	24 assays	EUR 547.2
Description: CytoSelect 96-Well Cell Transformation Assays (Cell Recovery Compatible) provide a robust system for detecting transformed cells, screening cell transformation inhibitors, and determining in vitro drug sensitivity. A proprietary modified soft agar matrix allows you to either quantify cells using the included fluorescent dye, or recover the cells for further analysis.

Tissue, Membrane Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima)
MBS639777-01mg	MyBiosource	0.1mg	EUR 570

Tissue, Membrane Protein, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima)
MBS639777-5x01mg	MyBiosource	5x0.1mg	EUR 2345

STAT3 Reporter (Luc) - HEK293 Cell line (Puromycin)
79800-P	BPS Bioscience	2 vials	EUR 3730
Description: The STAT3 Reporter (Luc)-HEK293 cell line is designed for monitoring STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines and growth factors, endogenous STAT3 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.

Luciferase Stable 17L3C (17L3C-luc) Cell Line
T6240	ABM	1x10^6 cells / 1.0 ml	EUR 3950

Collagen-based Cell Contraction Assay
CBA-201	Cell Biolabs	24 assays	EUR 420

Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line
60628	BPS Bioscience	2 vials	EUR 7645
Description: Human Foxp3 luciferase reporter construct is stably integrated into the genome of Jurkat T- cells. The firefly luciferase gene is controlled by a human Foxp3 promoter and an enhancer-like conserved noncoding sequence upstream of the Foxp3 promoter.

NF- κB Reporter (Luc) - Raw 264.7 Cell line
79978	BPS Bioscience	2 vials	EUR 2045
Description: The NF-κB reporter (Luc)-Raw 264.7 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

PAI-1 Report Cell Line (Luc)-Mv1 Lu
ABC-RC199D	AcceGen	1 vial	Ask for price
Description: PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression.PAI-1 Reporter (Luc) –Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity.

Radius 384-Well Cell Migration Assay
CBA-127	Cell Biolabs	384 assays	EUR 721.2
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

Radius 384-Well Cell Migration Assay
CBA-127-5	Cell Biolabs	5 x 384 wells	EUR 2802
Description: The Radius Cell Migration Assay provides a unique alternative to conventional cell migration assays using the Boyden chamber. Unlike Boyden chamber assays which may only be analyzed at endpoint, the Radius assay uses a proprietary cell culture plate containing a carefully-defined biocompatible hydrogel (Radius gel) spot centralized at the bottom of each well. When cells are seeded in the well, they will attach everywhere except on the Radius gel, creating a cell-free zone. Following cell seeding the Radius gel is removed, allowing migratory cells to move across the area and close the gap.

NF- κB Reporter (Luc) - THP-1 Cell Line
79645	BPS Bioscience	2 vials	EUR 1900
Description: The NF-κB reporter (Luc)-THP-1 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

HIF-1 Alpha Cell Based ELISA Kit
CBA-281	Cell Biolabs	96 assays	EUR 734.4
Description: Cell Biolabs? HIF-1 Cell Based ELISA Kit is an immunoassay developed for rapid detection of HIF-1 Alpha in fixed cells. Cells on a microplate are stimulated for HIF-1 Alpha stabilization, fixed, permeabilized, and then neutralized in the well. HIF-1 Alpha is then detected with an anti-HIF-1 alpha antibody followed by an HRP conjugated secondary antibody. Each kit provides sufficient reagents to perform up to a total of 96 assays and can detect HIF-1 Alpha from human, mouse, or rat.

CytoSelect™ MTT Cell Proliferation Assay
CBA-252	Cell Biolabs	960 assays	EUR 320

PAI-1 Reporter (Luc) - Mv1 Lu Cell Line
60544	BPS Bioscience	2 vials	EUR 3595
Description: PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression._x000D__x000D_PAI-1 Reporter (Luc) -Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity. _x000D_

NF-κB reporter (Luc) - NIH/3T3 Cell line
79469	BPS Bioscience	2 vials	EUR 1900
Description: The NF-κB reporter (Luc)-NIH/3T3 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

Radius™ 24-Well Cell Migration Assay
CBA-125	Cell Biolabs	24 assays	EUR 425

Radius™ 24-Well Cell Migration Assay
CBA-125-5	Cell Biolabs	5 x 24 assays	EUR 1820

Radius™ 96-Well Cell Migration Assay
CBA-126	Cell Biolabs	96 assays	EUR 495

Radius™ 96-Well Cell Migration Assay
CBA-126-5	Cell Biolabs	5 x 96 assays	EUR 2095

Radius™ 48-Well Cell Migration Assay
CBA-5037	Cell Biolabs	48 assays	EUR 445

Radius™ 48-Well Cell Migration Assay
CBA-5037-5	Cell Biolabs	5 x 48 assays	EUR 1895

NF-κB Reporter (Luc) - CHO-K1 Cell Line
60622	BPS Bioscience	2 vials	EUR 1095
Description: An NF-κB luciferase reporter construct is stably integrated into the genome of CHO-K1 cells. The firefly luciferase gene is controlled by the NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene._x000D_The NF-κB-luciferase / CHO-K1 cell line is suitable for monitoring the activity of NF-κB transcription factor through luminescence readout.). This cell line responds to human cytokine IL-1β, responds moderately to human TNF, and does not respond to human IFN-λ (2 µg/ml). Reducing the amount of serum during incubation period may increase the sensitivity to cytokines. Since CHO-K1 cells do not express endogenous human proteins, this cell line provides an excellent platform to enable exogenous expression of a protein of interest to study its downstream effect on NF-κB signaling.

CD40/NF-κB Report Cell Line(Luc) - HEK293
ABC-RC111D	AcceGen	1 vial	Ask for price
Description: Recombinant HEK293 cell line expressing full length human CD40 (Tumor necrosis factor receptor superfamily member 5; TNFRSF5). Expression is confirmed by real-time qPCR and Western Blot. This NF-ĸB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-andkappa;B response element located upstream of the TATA promoter. Following activation by human CD40 ligand, NF-ĸB transcription factor binds to the DNA response elements to induce transcription of the luciferase gene.

CytoSelect Cell Proliferation Assay Reagent (Fluorometric)
CBA-250	Cell Biolabs	10 mL	EUR 490.8
Description: Cell Biolabs? CytoSelect Cell Proliferation Assay Reagent (Fluorometric) provides a fluorometric format for measuring and monitoring cell proliferation. Cells can be plated and then treated with compounds or agents that affect proliferation.  Cells are then incubated with the proliferation reagent.  Upon entering metabolically active live cells, the non-fluorescent proliferation reagent is converted into a bright red fluorescent form. An increase in cell proliferation is accompanied by increased fluorescent signal, while a decrease in cell proliferation (and signal) can indicate the toxic effects of compounds or suboptimal culture conditions.  The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues.  This cell proliferation reagent can be used to detect proliferation in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells. The kit contains sufficient reagents for the evaluation of 960 assays in ten 96-well plates or 192 assays in eight 24-well plates.

CytoSelect™ BrdU Cell Proliferation ELISA Kit
CBA-251	Cell Biolabs	96 assays	EUR 455

CytoSelect™ 96-well Cell Transformation Assay
CBA-130	Cell Biolabs	96 assays	EUR 640

CytoSelect™ 96-well Cell Transformation Assay
CBA-130-5	Cell Biolabs	5 x 96 assays	EUR 2695

NF-κB Reporter (Luc) - A549 Stable Cell Line
60625	BPS Bioscience	2 vials	EUR 1915
Description: NF-κB luciferase reporter construct is stably integrated into the genome of A549 cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.

STAT5 Reporter (Luc)- U937 Cell Line (GM-CSF)
79941	BPS Bioscience	2 vials	EUR 1980
Description: The STAT5 Reporter (Luc)-U937 cell line is designed for monitoring STAT5 signal transduction pathway in the U937 cell line. It contains a firefly luciferase gene driven by the STAT5 response element located upstream of the minimal TATA promoter. After activation by GM-CSF, endogenous STAT5 binds to the DNA response elements, inducing transcription of the luciferase reporter gene.

CytoSelect™ Cell Viability and Cytotoxicity Assay
CBA-240	Cell Biolabs	96 assays	EUR 305

Tissue, Total RNA, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinoma), BioGenomics
MBS638573-005mg	MyBiosource	0.05mg	EUR 485

Tissue, Total RNA, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinoma), BioGenomics
MBS638573-5x005mg	MyBiosource	5x0.05mg	EUR 1960

CytoSelect 24-well Laminin Cell Invasion, Colorimetric
CBA-110-LN	Cell Biolabs	12 assays	EUR 714
Description: The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the morbidity and mortality of cancers. Cell invasion requires several distinct cellular functions including adhesion, motility, detachment, and extracellular matrix proteolysis. Our CytoSelect Cell Invasion Assays utilize precoated inserts to assay the invasive properties of tumor cells. Invasive cells can be quantified in 24-well plates on either a standard microplate reader or a fluorescence plate reader. Inserts are precoated on the top of the membrane with Laminin.

CytoSelect™ 24-Well Cell Co-Culture System
CBA-160	Cell Biolabs	24 assays	EUR 365

CytoSelect™ 24-Well Cell Co-Culture System
CBA-160-5	Cell Biolabs	5 x 24 assays	EUR 1585

CytoSelect™ 48-Well Cell Contraction Assay Kit
CBA-5021	Cell Biolabs	48 assays	EUR 575

CytoSelect 384-well Cell Transformation Assay, Fluorometric
CBA-145	Cell Biolabs	384 assays	EUR 1208.4
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader.

CytoSelect 384-well Cell Transformation Assay, Fluorometric
CBA-145-5	Cell Biolabs	5 x 384 assays	EUR 4681.2
Description: Our CytoSelect 384-Well Cell Transformation Assay uses a modified soft agar 3D matrix to support the formation of colonies by neoplastic cells. Quantitation of cell transformation is performed on a fluorescence plate reader.

CytoSelect™ Cell Proliferation Assay Reagent (Colorimetric)
CBA-253	Cell Biolabs	10 mL	EUR 320

Tissue, Genomic DNA, Human Tumor Cell Line, MCF 7 (Human Breast Adenocarcinima), BioGenomics
MBS654437-01mg	MyBiosource	0.1mg	EUR 505