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Simulation of oral absorption from non-bioequivalent dosage forms of the salt of raltegravir, a poorly soluble acidic drug, using a physiologically based biopharmaceutical modeling (PBBM) approach

Simulation of oral absorption from non-bioequivalent dosage forms of the salt of raltegravir, a poorly soluble acidic drug, using a physiologically based biopharmaceutical modeling (PBBM) approach

Non-bioequivalent plasma focus profiles amongst totally different dosage types of the salt of raltegravir, a poorly soluble acidic drug, had been investigated utilizing biorelevant in vitro testing mixed with the business in silico software program, Simcyp┬«. A suspension and a pill dosage types of raltegravir potassium had been chosen because the take a look at […]